| Document ID (ISN) | 57222 |
| CIS number |
92-237 |
| ISSN - Serial title |
0355-3140 - Scandinavian Journal of Work, Environment and Health |
| Year |
1990 |
| Convention or series no. |
|
| Author(s) |
Partanen T., Kauppinen T., Hernberg S., Nickels J., Luukkonen R., Hakulinen T., Pukkala E. |
| Title |
Formaldehyde exposure and respiratory cancer among woodworkers - An update |
| Bibliographic information |
Dec. 1990, Vol.16, No.6, p.394-400. 21 ref. |
| Abstract |
Respiratory cancer was examined in relation to occupational formaldehyde exposure in a case-referent study (136 cases, 408 referents) nested in a woodworker cohort. Plant- and time-specific job-exposure matrices were constructed for formaldehyde exposure. Over 3ppm-months of formaldehyde exposure was associated with an odds ratio of 1.4 [90% confidence interval (90% CI) 0.5-4.1]. The odds ratios for lung cancer were near unity, the excess risk concentrating on the upper respiratory tract. The odds ratios for combined formaldehyde-phenol exposure (all respiratory cancers) was 1.6 (90% CI 0.6-4.4) but 1.0 for formaldehyde only. No consistent exposure-response patterns emerged for the level, duration, or cumulative exposure. The results are hardly more than debatable support for the hypothesis concerning formaldehyde as a carcinogen in humans, the possible risk seemingly concentrating on the upper respiratory tract rather than the lung. |
| Descriptors (primary) |
formaldehyde; laryngeal cancer; woodworking industry; lung cancer; carcinogenic effects; respiratory diseases |
| Descriptors (secondary) |
phenol; comparative study; dose-response relationship; epidemiologic study |
| Document type |
D - Periodical articles |
| Country / State or Province | Finland |
| Subject(s) |
Woodworking industry
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Lumber and the woodworking industry
Diseases of the respiratory system (except for pneumoconiosis & similar)
Aldehydes
Woodworking industry
|
