Document ID (ISN) | 56946 |
CIS number |
91-1932 |
ISSN - Serial title |
0002-8894 - American Industrial Hygiene Association Journal |
Year |
1991 |
Convention or series no. |
|
Author(s) |
Kononen D.W. |
Title |
First-year changes in blood lead and zinc protoporphyrin levels within two groups of occupational lead workers |
Bibliographic information |
Apr.1991, Vol.52, No.4, p.177-182. Illus. 9 ref. |
Abstract |
Quarterly changes in the blood lead (PbB) and zinc protoporphyrin (ZPP) levels of 30 male lead-acid storage battery workers and 24 auto assembly workers during their first year of lead exposure are described. The greatest absolute and percentage increases above baseline PbB levels occurred during the first 3 months of continuous exposure when battery and assembly workers' average PbB levels increased by 99% and 134% respectively. Mean ZPP levels increased steadily through the first 3 quarters of exposure for both groups of workers before declining slightly in the last quarter. The PbB-ZPP dose-effect relationship is characterised through the simple linear regression of log-transformed ZPP versus PbB levels. Dose-response modeling of each quarter's PbB-ZPP data was performed using probit analysis. These observed PbB and ZPP changes illustrate the time lag in the appearance of ZPP following introduction to lead-related work. |
Descriptors (primary) |
lead; storage batteries; motor vehicle industry; exposure; determination in blood; blood monitoring; zinc and compounds; length of exposure |
Descriptors (secondary) |
effective dose 50; mathematical models; dose-response relationship; zinc |
Document type |
D - Periodical articles |
Country / State or Province | USA |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Inorganic substances Biological monitoring Motor vehicle manufacturing industry Lead and compounds
|