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Document ID (ISN)56598
CIS number 91-1584
ISSN - Serial title Japanese Journal of Traumatology and Occupational Medicine
Year 1991
Convention or series no.
Author(s) Morinaga K., Sakatani M., Yokoyama K., Yasui I., Hara I., Sera Y.
Title Silicosis and lung cancer - A retrospective cohort study of compensated patients with silicosis in Osaka
Original title Keihai to haigan: Ōsaka ni okeru keihai nintei kanja no kohōto kenkyū [in Japanese]
Bibliographic information 1 Mar. 1991, Vol.39, No.3, p.192-197. 24 ref.
Abstract A retrospective cohort study was conducted on 248 male silicotics who were approved as total disability or complicating disease compensation recipients between 1972 and 1976 in Osaka Prefecture (Japan). At the end of 1987, 76 were dead. The standardised mortality ratio (SMR) was calculated for 226 patients who survived for more than 3yrs from the date of health examination for compensation, based on the mortality rates of the Osaka population. SMR for all causes was 0.98 (55), but those for tuberculosis, lung cancer and respiratory diseases were 9.79 (14), 3.70 (10), and 4.11 (18) respectively, all statistically significant. Of 15 cases with lung cancer, including 5 cases of death within the 3-year observation period, 8 were squamous cell carcinomas, 2 small cell carcinomas, 1 undifferentiated type, 2 adenocarcinomas, and 2 unknown. Excluding 4 cases with unknown smoking history, all were smokers and ex-smokers. Thus, a large part of the lung cancer in this cohort was closely associated with smoking, but the observed excess risk may not be accounted for solely by smoking.
Descriptors (primary) Japan; silicosis; lung cancer; smoking
Descriptors (secondary) risk factors; epidemiologic study
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Dust, aerosols and related diseases
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)