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Document ID (ISN)56486
CIS number 91-1278
ISBN(s) 90-5307-163-6
Year 1991
Convention or series no. Arbeidsinspectie RA 3/91
Author(s)
Werkgroep van Deskundigen ter vaststelling van MAC-waarden (Dutch Expert Committee for Occupational Standards)
Title Health-based recommended occupational exposure limits for diisocyanates
Bibliographic information Department of Social Affairs and Employment, Directorate-General of Labour (Ministerie van Sociale Zaken en Werkgelegenheid, Directoraat-Generaal van de Arbeid), Postbus 90804, 2509 LV Den Haag, Netherlands, 1991. 70p. 123 ref.
Abstract Evaluation of the risks to human health of exposure to diisocyanates: TDI (toluene diisocyanate), MDI (diphenylmethane diisocyanate), HDI (hexamethylene diisocyanate), NDI (naphthylene diisocyanate) and IPDI (isophorone diisocyanate). Attention is given to: production, uses and occurrences; environmental and biological monitoring; occupational exposure limits in various countries; toxicokinetics; toxic effects (acute toxicity, long-term toxicity/carcinogenicity). Analysis of the data available led to the following recommended occupational exposure limits: TDI: 36g/m3 (5ppb) TWA-8h, 145g/m3 (20ppb) TWA-15min; MDI: 52 g/m3 (5ppb) TWA-8h, 208g/m3 (20ppb) TWA-15min; HDI: 35g/m3 (5ppb) TWA-8h, 140g/m3 (20ppb) TWA-15min; NDI: 44g/m3 (5ppb) TWA-8h, 175g/m3 (20ppb) TWA-15min; IPDI: 46g/m3 (5ppb) TWA-8h, 185g/m3 (20ppb) TWA-15min. Summary in Dutch.
Descriptors (primary) threshold limit values; diphenylmethane diisocyanate; Netherlands; isocyanates; biological effects; isophorone diisocyanate; naphthylene diisocyanate; tolylene diisocyanate; determination of exposure limits; hexamethylene diisocyanate
Descriptors (secondary) literature survey; report; criteria document; 2,4-tolylene diisocyanate; toxicity evaluation; 2,6-tolylene diisocyanate
Document type E - Books, reports, proceedings
Country / State or ProvinceNetherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits
Isocyanates
Cyano compounds