| Document ID (ISN) | 56266 |
| CIS number |
91-1203 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
1990 |
| Convention or series no. |
|
| Author(s) |
Leung H.W., Paustenbach D.J. |
| Title |
Organic acids and bases: review of toxicological studies |
| Bibliographic information |
1990, Vol.18, No.6, p.717-735. Illus. 98 ref. |
| Abstract |
Organic acids and bases are among the most frequently used chemicals in the manufacturing industries. However, only a few have had a full toxicological evaluation and even fewer have had occupational exposure limits established. The paper reviews the acute and chronic toxicity data of organic acids and bases, and considers the mechanism by which these chemicals produce their effects. A methodology for establishing preliminary occupational exposure limits based on the physicochemical properties of these chemicals is presented. Workplace exposure limits for 20 organic acids and bases which currently have no exposure guidelines are suggested. Advice regarding appropriate medical treatment of exposure to these substances is discussed. |
| Descriptors (primary) |
toxic effects; threshold limit values; acute toxicity; amines; chronic toxicity; toxicology; permissible levels; toxicity evaluation; organic acids |
| Descriptors (secondary) |
literature survey; propionic acid; triethylenetetramine; formic acid; acetic acid; butyric acid; medical treatment; caproic acid; heptanoic acid; caprylic acid; diethylenetriamine; cyclohexylamine; lethal dose 50; valeric acid |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Occupational exposure limits
Organic acids
|
