|Document ID (ISN)||55720|
|Convention or series no.
U.S. Environmental Protection Agency
||Development toxicology: Risk assessment and the future
||Van Nostrand Reinhold, 115 Fifth Ave., New York, NY 10003, USA; Chapman and Hall, 11 New Fetter Lane, London EC4P 4EE, United Kingdom, Dec. 1989. 279p. Illus. Approx. 810 ref. Index. Price: GBP 32.50.
||Review of efforts to estimate the risk of developmental defects and disabilities in humans due to the exposure of parents to chemicals before conception, during pregnancy or during childhood. Emphasis is on areas of needed research identified by the US Environmental Protection Agency, including paternally mediated effects, nonbehavioural functional effects, pharmacokinetic and physiological models, structure-activity relationships and mathematical modelling. Carcinogenicity, interspecies differences and methodological issues are also discussed.
||antifertility effects; USA; toxicology; neoplasms; gonadotropic effects; teratogenic effects; hazard evaluation
||embryotoxic effects; literature survey; extrapolation animal man; prediction formulae; neuropsychic effects; carcinogenic effects; mathematical models; genetic effects
||E - Books, reports, proceedings
|Country / State or Province||USA|
|Broad subject area(s)
||Antifertility and prenatal effects
Genetic factors in reaction to exposures