|Document ID (ISN)||55702|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Tornling G., Alexandersson R., Hedenstierna G., Plato N.
||Decreased lung function and exposure to diisocyanates (HDI and HDI-BT) in car repair painters: observations on re-examination 6 years after initial study
||1990, Vol.17, No.3, p.299-310. Illus. Bibl.ref.
||36 car painters and 115 control persons participated in a follow-up investigation 6 years after the initial study, including measurement of lung function and estimation of exposure to diisocyanates. The mean exposure for the car painters was 0.0015mg/m3 hexamethylenediisocyanate (HID) and 0.09mg/m3 hexamethylenediisocyanate-biurettrimer (HID-BT), but frequently there were peak exposures exceeding 2.0mg/m3 HDI-BT for at least 30sec. Compared with smoking controls, the smoking car painters had greater yearly reduction in FVC (95 versus 38mL), FEV1 (61 versus 28mL), and VC (77 versus 30mL). The nonsmoking car painters showed no differences in lung volumes compared with their nonsmoking controls. The impairment correlated well with the frequency of high peak exposures to HDI-BT, but not with the mean exposure to diisocyanates.
||hexamethylene diisocyanate; hexamethylene diisocyanate biuret; respiratory impairment; painting; exposure evaluation; toxic substances
||smoking; respiratory volume; comparative study; respiratory function tests; epidemiologic study
||D - Periodical articles
|Country / State or Province||Sweden|
|Broad subject area(s)
||Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)