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CISDOC database

Document ID (ISN)55702
CIS number 91-453
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1990
Convention or series no.
Author(s) Tornling G., Alexandersson R., Hedenstierna G., Plato N.
Title Decreased lung function and exposure to diisocyanates (HDI and HDI-BT) in car repair painters: observations on re-examination 6 years after initial study
Bibliographic information 1990, Vol.17, No.3, p.299-310. Illus. Bibl.ref.
Abstract 36 car painters and 115 control persons participated in a follow-up investigation 6 years after the initial study, including measurement of lung function and estimation of exposure to diisocyanates. The mean exposure for the car painters was 0.0015mg/m3 hexamethylenediisocyanate (HID) and 0.09mg/m3 hexamethylenediisocyanate-biurettrimer (HID-BT), but frequently there were peak exposures exceeding 2.0mg/m3 HDI-BT for at least 30sec. Compared with smoking controls, the smoking car painters had greater yearly reduction in FVC (95 versus 38mL), FEV1 (61 versus 28mL), and VC (77 versus 30mL). The nonsmoking car painters showed no differences in lung volumes compared with their nonsmoking controls. The impairment correlated well with the frequency of high peak exposures to HDI-BT, but not with the mean exposure to diisocyanates.
Descriptors (primary) hexamethylene diisocyanate; hexamethylene diisocyanate biuret; respiratory impairment; painting; exposure evaluation; toxic substances
Descriptors (secondary) smoking; respiratory volume; comparative study; respiratory function tests; epidemiologic study
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Exposure evaluation
Cyano compounds
Surface treatment