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Document ID (ISN)55694
CIS number 91-546
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1990
Convention or series no.
Author(s) Deschamps D., Leport M., Laurent A.M., Cordier S., Festy B., Conso F.
Title Toxicity of ethylene oxide on the lens and on leucocytes: an epidemiological study in hospital sterilisation installations
Bibliographic information May 1990, Vol.47, No.5, p.308-313. Illus. 13 ref.
Abstract An epidemiological study was conducted in 55 subjects (mean age: 41) in hospitals to determine the prevalence of lens opacities and cataracts in workers exposed to ethylene oxide in six sterilisation units. The relation between occupational exposure to ethylene oxide and white blood cell concentrations was also investigated. Lens opacities were observed in 19 of the 55 exposed. No link was found between the characteristics of the lens opacities and the characteristics of exposure. For cataracts, their prevalence differed significantly between the exposed (six of 21) and the non-exposed (0 of 16); there was no relation between their existence and overexposures. The risk of lens opacifications by ethylene oxide could also exist during chronic exposure to low concentrations. Linear relations were found between the logarithm of the cumulative exposure index and the logarithms of blood concentrations of polymorphoneutrophils.
Descriptors (primary) leukaemogenic effects; disinfection of equipment; cataractogenic effects; hospitals; ethylene oxide
Descriptors (secondary) comparative study; epidemiologic study
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Leukaemia
Diseases of the eye and vision damage
Ethylene oxide
Health care services