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Document ID (ISN)55560
CIS number 91-568
ISBN(s) 92-4-157110-1
Year 1990
Convention or series no. Environmental Health Criteria 110
Author(s)
International Programme on Chemical Safety (IPCS)
Title Tricresyl phosphate
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1990. 122p. 226 ref. Price: CHF 15.00; developing countries: CHF 10.50.
Abstract The ortho isomer of tricresyl phosphate (TOCP) and isomeric mixtures containing it are considered major hazards to human health. There have been numerous reported cases of poisoning due to contamination of foodstuffs, and occupational poisoning, usually resulting from dermal exposure, has also been reported. Short-term symptoms of ingestion involve vomiting, abdominal pain and diarrhoea, while characteristically delayed, longer-term symptoms are neurological, frequently leading to paralysis and pyramidal signs (spasticity, etc.). Irritant and allergic dermatitis have been reported. Because of the considerable variation among individuals in sensitivity to TOCP, it is not possible to establish a safe level of exposure and it is recommended that exposure should be minimised. Detailed summaries in French and Spanish.
Descriptors (primary) IPCS; WHO; phosphoric acid esters; environmental pollution; toxicology; hazard evaluation; triorthocresyl phosphate
Descriptors (secondary) toxic effects; poisoning; literature survey; ILO; tri-meta-cresyl phosphate; tri-p-tolyl phosphate; paresis; neurological effects; criteria document; UNEP
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
Esters and salts
Environmental pollution