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Document ID (ISN)55495
CIS number 91-671
Year 1988
Convention or series no.
Advisory Committee on Dangerous Pathogens
Title Inactivation of viral haemorrhagic fever specimens with B-propiolactone
Bibliographic information Health Services Division 1B, Room A414, Alexander Fleming House, Elephant and Castle, London SE1 6BY, United Kingdom, 1988. 14p. Illus. Bibl.
Abstract These guidelines describe how heparimised or EDTA treated blood specimens suspected of containing certain haemorrhagic fever viruses may be made safe for examination by inactivation with B propiolactone (BPL). Details are given of the characteristics of BPL and precautions to be taken during its use, and of the effect of BPL inactivation of blood on test results. Kits for blood specimen collection are described and a model information and instruction sheet provided for physicians submitting specimens for inactivation. Details are given of the inactivation procedure and the materials required, and accident procedures are outlined for cases of inoculation accident or spillage.
Descriptors (primary) blood; United Kingdom; biological hazards; virus diseases; health services; propiolactone
Descriptors (secondary) description of equipment; taking of samples; emergency treatment; description of technique; health care personnel; chemical hazards; hospitals
Document type E - Books, reports, proceedings
Country / State or ProvinceUnited Kingdom
Subject(s) Toxic and dangerous substances
Broad subject area(s) Biological hazards
Browse category(ies) Viral diseases (other than aids)
Health care services
Biological hazards
Bacterial and parasitic diseases