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CISDOC database

Document ID (ISN)55488
CIS number 91-540
ISSN - Serial title Polish Journal of Occupational Medicine
Year 1989
Convention or series no.
Author(s) Paradowski M., Roczek E., Tkacz B., Dworniak D.
Title Increase in antipyrine clearance in workers exposed to phenol and toluene in the petrochemical industry
Bibliographic information Mar. 1989, Vol.2, No.3, p.229-237. Illus. 10 ref.
Abstract In 90 workers of the petrochemical industry occupationally exposed to a mixture of petroleum derivatives, including 60 persons exposed mainly to phenol and 30 to toluene, the metabolic activity of the liver was examined using the antipyrine test. In both groups of subjects, an increase of antipyrine clearance in saliva was observed. Occupational exposure to lipophylic derivatives of petroleum seems to induce the function of liver microsomal enzymes.
Descriptors (primary) phenol; toluene; enzyme disturbances; toxicology; petrochemical industry; metabolic disturbances; petrochemicals; exposure evaluation; hepatic disorders
Descriptors (secondary) Poland; medical examinations; epidemiologic study
Document type D - Periodical articles
Country / State or ProvincePoland
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Blood diseases
Endocrine diseases
Exposure evaluation
Phenols and phenolic compounds
Petrochemical industry
Alcohols
Aromatic hydrocarbons
Chemical industry