Document ID (ISN) | 55336 |
CIS number |
91-225 |
ISBN(s) |
92-4-157109-8 |
Year |
1990 |
Convention or series no. |
Environmental Health Criteria 109
|
Author(s) |
International Programme on Chemical Safety (IPCS) |
Title |
Summary report on the evaluation of short-term tests for carcinogens (Collaborative study on In Vivo Tests) |
Bibliographic information |
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1990. 96p. Illus. 15 ref. Price: CHF 13.00. |
Abstract |
This IPCS report describes criteria for the selection of an appropriate short-term in vivo test to determine the in vivo activity of established genotoxins and the selection of 4 test chemicals, the assays used, and the results of tests carried out on the selected chemicals. An assessment is made of the performance of the assays along with a selection of those considered to be most effective. Short-term in vivo tests have a vital role to play in the identification of those chemicals most likely to present a carcinogenic/mutagenic hazard. Detailed summaries in French and Spanish. |
Descriptors (primary) |
mutagens; carcinogens; IPCS; carcinogenicity tests; hazard evaluation; mutagenicity tests; WHO |
Descriptors (secondary) |
ILO; UNEP; pyrene; evaluation of technique; 4-acetylaminofluorene; benzo(a)pyrene; 2-acetylaminofluorene |
Document type |
E - Books, reports, proceedings |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Risk evaluation
|