ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)55336
CIS number 91-225
ISBN(s) 92-4-157109-8
Year 1990
Convention or series no. Environmental Health Criteria 109
International Programme on Chemical Safety (IPCS)
Title Summary report on the evaluation of short-term tests for carcinogens (Collaborative study on In Vivo Tests)
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1990. 96p. Illus. 15 ref. Price: CHF 13.00.
Abstract This IPCS report describes criteria for the selection of an appropriate short-term in vivo test to determine the in vivo activity of established genotoxins and the selection of 4 test chemicals, the assays used, and the results of tests carried out on the selected chemicals. An assessment is made of the performance of the assays along with a selection of those considered to be most effective. Short-term in vivo tests have a vital role to play in the identification of those chemicals most likely to present a carcinogenic/mutagenic hazard. Detailed summaries in French and Spanish.
Descriptors (primary) mutagens; carcinogens; IPCS; carcinogenicity tests; hazard evaluation; mutagenicity tests; WHO
Descriptors (secondary) ILO; UNEP; pyrene; evaluation of technique; 4-acetylaminofluorene; benzo(a)pyrene; 2-acetylaminofluorene
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation