ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)55124
CIS number 91-122
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1988
Convention or series no.
Author(s) Stel'mah V.A.
Title Toxicologie characteristics and nature of combined effect of a mixture of orthomenthane hydrocarbons
Original title Toksikologičeskie svojstva i harakter kombinirovannogo dejstvija smesi ortomentanovyh uglevodorodov [in Russian]
Bibliographic information Sep. 1988, No.9, p.34-37. 9 ref.
Abstract B-100, a plant growth regulator preparation, is a mixture of o-methane, o-mentha-1,4-diene and o-cymene (o-methylcumene). Its intragastric LD50 for mice was 4950 (3960-6190)mg/kg and 5100 (4200-6300)mg/kg for rats. It had slight cumulative, mild local irritating, skin-resorptive effects and effects on mucous membranes. Combined effects were analysed by linear regression using a computer. The combined effect was less than additive under the conditions of intragastric administration and additive in the case of inhalation. Thus, for establishing an exposure limit for B-100, all 3 components can be considered equivalent.
Descriptors (primary) agricultural chemicals; o-methylcumene; o-mentha-1,4-diene; synergism; o-menthene; toxicology
Descriptors (secondary) toxicity evaluation; inhalation toxicity; lethal dose 50; animal experiments
Document type D - Periodical articles
Country / State or ProvinceUSSR
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Agricultural chemicals
Aromatic hydrocarbons
Aliphatic and alicyclic hydrocarbons