|Document ID (ISN)||55124|
|ISSN - Serial title
||Gigiena truda i professional'nye zabolevanija
|Convention or series no.
||Toxicologie characteristics and nature of combined effect of a mixture of orthomenthane hydrocarbons
||Toksikologičeskie svojstva i harakter kombinirovannogo dejstvija smesi ortomentanovyh uglevodorodov [in Russian]|
||Sep. 1988, No.9, p.34-37. 9 ref.
||B-100, a plant growth regulator preparation, is a mixture of o-methane, o-mentha-1,4-diene and o-cymene (o-methylcumene). Its intragastric LD50 for mice was 4950 (3960-6190)mg/kg and 5100 (4200-6300)mg/kg for rats. It had slight cumulative, mild local irritating, skin-resorptive effects and effects on mucous membranes. Combined effects were analysed by linear regression using a computer. The combined effect was less than additive under the conditions of intragastric administration and additive in the case of inhalation. Thus, for establishing an exposure limit for B-100, all 3 components can be considered equivalent.
||agricultural chemicals; o-methylcumene; o-mentha-1,4-diene; synergism; o-menthene; toxicology
||toxicity evaluation; inhalation toxicity; lethal dose 50; animal experiments
||D - Periodical articles
|Country / State or Province||USSR|
|Broad subject area(s)
||Occupational medicine, epidemiology
Aliphatic and alicyclic hydrocarbons