|Document ID (ISN)||54877|
|Convention or series no.
||CONCAWE Report No.8/89
||Health risk of exposure to non-occupational sources of benzene
||Oil Companies European Organisation for Environmental and Health Protection, CONCAWE, 30-9A Koningin Julianaplein, 2595 AA Den Haag, Netherlands, 1989. 15p. 24 ref.
||Repeated exposure to high concentrations of benzene is associated with the onset of leukaemia, and benzene is therefore classified as a human carcinogen. However, no case of benzene-induced leukaemia has been confirmed following repeated exposure at work to benzene at concentrations below 100ppm. Benzene also causes depression of blood formation, but again no case of benzene-induced depression of blood formation has been confirmed at below 25 to 30ppm. Benzene causes chromosal aberrations, but there is no evidence to link these with the occurrence of leukaemia. A maximum permissible time weighted average workplace exposure for benzene of 5ppm and an action level of 1.5ppm have been proposed in the EC.
||carcinogens; health hazards; hazard evaluation; benzene
||leukaemia; limitation of exposure; exposure evaluation; diseases of blood-forming organs; environmental pollution; replaced; criteria document; chromosome changes
||F - Information notes, codes of practice, standards
|Country / State or Province||Netherlands|
||Toxic and dangerous substances
|Broad subject area(s)
Genetic factors in reaction to exposures