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Document ID (ISN)54646
CIS number 90-1573
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1989
Convention or series no.
Author(s) Ormerod A.D., Wakeel R.A., Mann T.A.N., Main R.A., Aldrige R.D.
Title Polyamine sensitization in offshore workers handling drilling muds
Bibliographic information Nov. 1989, Vol.21, No.5, p.326-329. 3 ref.
Abstract Oil-based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud we have identified polyamine (diethylenetriamine and triethylenetetramine) sensitivity in 5 patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross-linked fatty acid amido-amines, in which unreacted amine groups are thought to cross-sensitise with these constituent polyamines. Cross-reactivity between ethylenediamine, diethyleneamine and triethylenetetramine was found in 9 subjects.
Descriptors (primary) triethylenetetramine; diethylenetriamine; ethylenediamine; offshore oil extraction; skin diseases; eczema; drilling machines; emulsifiers
Descriptors (secondary) dangerous substances
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Skin diseases
Aliphatic amines
Petroleum and natural gas industry