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Document ID (ISN)54278
CIS number 90-1280
ISSN - Serial title 0019-8366 - Industrial Health
Year 1988
Convention or series no.
Author(s) Zhou S.Y., Ziang Y.X., Chen Z.Q., Wang Y.Z.
Title Effects of occupational exposure to low-level carbon disulfide (CS2) on menstruation and pregnancy
Bibliographic information Apr. 1988, Vol.26, No.4, p.203-204. 14 ref.
Abstract In a retrospective cohort study, 265 female workers exposed to CS2 and 291 non-exposed female workers, as well as 530 pregnancies, were investigated with regard to the status of menstruation and the term and outcome of pregnancy. The average CS2 concentration to which the workers had been exposed for the 15 years prior to the study was 1.7-14.8mg/m3. Exposed female workers had a higher incidence rate of menstrual disturbance than non-exposed women (35.9% vs. 18.2%, relative risk = 2.0, p<0.01), and there was an exposure-response relationship between the CS2 level and the incidence rate of menstrual disturbance. There was no significant difference between the exposed and non-exposed groups in terms of rates of toxaemia, emesis gravidarum, spontaneous abortion, stillbirth, premature and overdue delivery, or congenital malformation. Thus, exposure to CS2 at around 10mg/m3 may affect the function of the female reproductive system.
Descriptors (primary) antifertility effects; viscose rayon industry; expectant mothers; menstrual disorders; exposure evaluation; carbon disulfide
Descriptors (secondary) China; cellulosic fibres; comparative study; age; length of exposure; toxic substances
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the reproductive system
Antifertility and prenatal effects
Inorganic sulfur compounds
Genetic factors in reaction to exposures
Inorganic substances
Exposure evaluation