|Document ID (ISN)||54278|
|ISSN - Serial title
||0019-8366 - Industrial Health
|Convention or series no.
||Zhou S.Y., Ziang Y.X., Chen Z.Q., Wang Y.Z.
||Effects of occupational exposure to low-level carbon disulfide (CS2) on menstruation and pregnancy
||Apr. 1988, Vol.26, No.4, p.203-204. 14 ref.
||In a retrospective cohort study, 265 female workers exposed to CS2 and 291 non-exposed female workers, as well as 530 pregnancies, were investigated with regard to the status of menstruation and the term and outcome of pregnancy. The average CS2 concentration to which the workers had been exposed for the 15 years prior to the study was 1.7-14.8mg/m3. Exposed female workers had a higher incidence rate of menstrual disturbance than non-exposed women (35.9% vs. 18.2%, relative risk = 2.0, p<0.01), and there was an exposure-response relationship between the CS2 level and the incidence rate of menstrual disturbance. There was no significant difference between the exposed and non-exposed groups in terms of rates of toxaemia, emesis gravidarum, spontaneous abortion, stillbirth, premature and overdue delivery, or congenital malformation. Thus, exposure to CS2 at around 10mg/m3 may affect the function of the female reproductive system.
||antifertility effects; viscose rayon industry; expectant mothers; menstrual disorders; exposure evaluation; carbon disulfide
||China; cellulosic fibres; comparative study; age; length of exposure; toxic substances
||D - Periodical articles
||Toxic and dangerous substances
|Broad subject area(s)
||Diseases of the reproductive system
Antifertility and prenatal effects
Inorganic sulfur compounds
Genetic factors in reaction to exposures