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CISDOC database

Document ID (ISN)54249
CIS number 90-1292
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1989
Convention or series no.
Author(s) T÷rnqvist M.┼., Almberg J.G., Bergmark E.N., Nilsson S., Osterman-Golkar S.M.
Title Ethylene oxide doses in ethene-exposed fruit store workers
Bibliographic information Dec. 1989, Vol.15, No.6, p.436-438. 17 ref.
Abstract Blood samples from 10 ethene-exposed fruit store workers and 10 referents were analysed for the level of hydroxyethyl adducts to N-terminal valine in haemoglobin (Hb). A statistically significant difference was obtained between the nonsmoking workers (N=7) and the nonsmoking referents (N=6). This finding demonstrates that ethene is metabolised to ethylene oxide in man. According to this preliminary study, ethene exposure at 0.3 (uncertainly range 0.1-1) ppm during workhours increases the adduct level by 23pmol/g Hb. This figure is compatible with a metabolic conversion of 3% (1-10%) of the inhaled ethene to ethylene oxide.
Descriptors (primary) metabolic process; ethylene; fruit processing and storing; ethylene oxide; inhalation
Descriptors (secondary) smoking; comparative study; haemoglobin monitoring; metabolic studies
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Ethylene oxide
Aliphatic and alicyclic hydrocarbons
Ethers