| Document ID (ISN) | 54148 |
| CIS number |
90-1283 |
| ISSN - Serial title |
0029-0440 - Niigata Medical Journal |
| Year |
1989 |
| Convention or series no. |
|
| Author(s) |
Sasagawa M. |
| Title |
Agricultural chemicals in cholesterol gallstones - with special reference to an epidemiological study on cancer of the biliary tract |
| Original title |
Tanno koresterōru kessekichū no zanryū nōyaku bunseki - tokuni tandōgan no ekigakuteki shiten kara [in Japanese] |
| Bibliographic information |
Feb. 1989, Vol.103, No. 2, p.104-111. Illus. 22 ref. |
| Abstract |
Niigata prefecture (Japan) has a very high mortality rate from biliary tract cancer. There is a correlation between the standardised mortality ratio (SMR) for biliary tract cancer and the amount of certain agricultural chemicals consumed. Agricultural chemicals were detected in cholesterol gallstones of 99 patients, including 11 patients with gallbladder cancer. DLD, pp'-DDT, β-BHC and PCB were detected in the gallstones, even though the epidemiological study showed no positive correlation between them and the SMR for biliary tract cancer. MCPA, MCPB, CNP and simetryn, which did show significant correlations with the SMR, were not detected. Further investigation of the biliary excretion of the metabolites of these chemicals is indicated. |
| Descriptors (primary) |
Japan; biliary tract diseases; neoplasms; pesticides; gallbladder diseases; mortality |
| Descriptors (secondary) |
epidemiologic study |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Agricultural chemicals
Gastrointestinal diseases
|
