|Document ID (ISN)||54131|
|ISSN - Serial title
||0105-1873 - Contact Dermatitis
|Convention or series no.
||Cavelier C., Foussereau J., Gille P., Zissu D.
||Allergy to nickel or cobalt: Tolerance to nickel and cobalt samples in man and in the guinea pig allergic or sensitized to these metals
||Aug. 1989, Vol.21, No.2, p.72-78. 14 ref.
||The aim of this study was to evaluate, in animals and humans sensitive to nickel or cobalt, the tolerance to manufactured metal samples of nickel and cobalt of a defined metallographic structure, plated or not with a layer of chrome or copper/chrome of a determined thickness. Under the defined experimental conditions, a guinea pig sensitised to one metal (nickel or cobalt) was intolerant to both metals (nickel and cobalt). A plating of chrome or copper/chrome did not act as a protection. In the human, it was not the same: the tolerance to metal samples was determined by the specific sensitivity. A plating of chrome or copper/chrome did not act as protection.
||cobalt; nickel; copper; sensitization; skin tests; chromium; skin allergies
||animal experiments; dangerous substances
||D - Periodical articles
||Toxic and dangerous substances
|Broad subject area(s)
Nickel and compounds
Copper and compounds