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Document ID (ISN)54131
CIS number 90-1269
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1989
Convention or series no.
Author(s) Cavelier C., Foussereau J., Gille P., Zissu D.
Title Allergy to nickel or cobalt: Tolerance to nickel and cobalt samples in man and in the guinea pig allergic or sensitized to these metals
Bibliographic information Aug. 1989, Vol.21, No.2, p.72-78. 14 ref.
Abstract The aim of this study was to evaluate, in animals and humans sensitive to nickel or cobalt, the tolerance to manufactured metal samples of nickel and cobalt of a defined metallographic structure, plated or not with a layer of chrome or copper/chrome of a determined thickness. Under the defined experimental conditions, a guinea pig sensitised to one metal (nickel or cobalt) was intolerant to both metals (nickel and cobalt). A plating of chrome or copper/chrome did not act as a protection. In the human, it was not the same: the tolerance to metal samples was determined by the specific sensitivity. A plating of chrome or copper/chrome did not act as protection.
Descriptors (primary) cobalt; nickel; copper; sensitization; skin tests; chromium; skin allergies
Descriptors (secondary) animal experiments; dangerous substances
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Allergies
Nickel and compounds
Copper and compounds
Inorganic substances