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Document ID (ISN)53784
CIS number 90-853
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1989
Convention or series no.
Author(s) Ames R.G., Brown S.K., Mengle D.C., Kahn E., Stratton J.W., Jackson R.J.
Title Cholinesterase activity depression among California agricultural pesticide applicators
Bibliographic information 1989, Vol.15, No.2, p.143-150. Bibl.
Abstract Cholinesterase activity measurements in California of 542 agricultural pesticide applicators under medical supervision during the first 9 months of 1985 were analysed. 26 workers, 4.8% of the sample, had cholinesterase values at or below the California threshold values for removal from continued exposure to cholinesterase inhibiting pesticides (60% of baseline for red blood cell cholinesterase and 50% of baseline for plasma cholinesterase activity). Eight of these 26 workers, 31.5% had pesticide-related illnesses. Pesticides most frequently associated with cholinesterase depressions exceeding California threshold values included mevinphos (Phosdrin), oxydemeton methyl (Metasystox-R), methomyl (Lannate), and acephate (Orthene); these pesticides included organophosphates in toxicity categories I and II and one carbamate in toxicity category I.
Descriptors (primary) cholinesterase monitoring; neurotoxic effects; methomyl; orthene; metasystox; occupation disease relation; pesticides; agricultural equipment; exposure evaluation; mevinphos
Descriptors (secondary) agricultural chemicals; dangerous substances; medical examinations; epidemiologic study; USA
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the nervous system
Biological monitoring
Esters and salts
Agricultural chemicals
Amides
Exposure evaluation