|Document ID (ISN)||53783|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Kadamani S., Asal N.R., Nelson R.Y.
||Occupational hydrocarbon exposure and risk of renal cell carcinoma
||1989, Vol.15, No.2, p.131-141. Bibl.
||A population-based case-control study (210 cases and 210 age- sex- and frequency-matched population controls) was conducted to evaluate the association between occupational hydrocarbon exposure and risk of renal cell carcinoma. Retrospective estimates of lifetime occupational hydrocarbon exposure were made and an exposure index was calculated based on time and score combinations. A weak positive association was found for hydrocarbon exposure in males only (odds ratio = 1.6). For those under the age of 60, exposure to moderate levels of hydrocarbons produced the highest risk, while for those over the age of 70 a dose-response relationship was found. Those overweight were at high risk for renal cell carcinoma, and there was positive interaction between hydrocarbon exposure and overweight. Alcohol use alone or in the presence of hydrocarbon exposure decreased the risk significantly.
||hydrocarbons; occupation disease relation; renal cancer; neoplasms; dose-response relationship; carcinogenic effects; petroleum and natural gas industry; exposure evaluation
||threshold limit values; dangerous substances; individual variables; comparative study; age; epidemiologic study; women; smoking
||D - Periodical articles
|Broad subject area(s)
||Occupational medicine, epidemiology
||Diseases of the kidney and the urinary system
Petroleum and natural gas industry