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Document ID (ISN)53783
CIS number 90-839
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1989
Convention or series no.
Author(s) Kadamani S., Asal N.R., Nelson R.Y.
Title Occupational hydrocarbon exposure and risk of renal cell carcinoma
Bibliographic information 1989, Vol.15, No.2, p.131-141. Bibl.
Abstract A population-based case-control study (210 cases and 210 age- sex- and frequency-matched population controls) was conducted to evaluate the association between occupational hydrocarbon exposure and risk of renal cell carcinoma. Retrospective estimates of lifetime occupational hydrocarbon exposure were made and an exposure index was calculated based on time and score combinations. A weak positive association was found for hydrocarbon exposure in males only (odds ratio = 1.6). For those under the age of 60, exposure to moderate levels of hydrocarbons produced the highest risk, while for those over the age of 70 a dose-response relationship was found. Those overweight were at high risk for renal cell carcinoma, and there was positive interaction between hydrocarbon exposure and overweight. Alcohol use alone or in the presence of hydrocarbon exposure decreased the risk significantly.
Descriptors (primary) hydrocarbons; occupation disease relation; renal cancer; neoplasms; dose-response relationship; carcinogenic effects; petroleum and natural gas industry; exposure evaluation
Descriptors (secondary) threshold limit values; dangerous substances; individual variables; comparative study; age; epidemiologic study; women; smoking
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the kidney and the urinary system
Petroleum and natural gas industry
Exposure evaluation