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Document ID (ISN)53680
CIS number 90-568
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1989
Convention or series no.
Author(s) Hausen B.M., Jensen S., Mohnert J.
Title Contact allergy to colophony - IV. The sensitising potency of commercial products - An investigation of French and American modified colophony derivatives
Bibliographic information Feb. 1989, Vol.20, No.2, p.133-143. Illus. 40 ref.
Abstract The sensitising capacity of 15 commercial colophony products was studied experimentally in guinea pigs. The study included 8 French and 6 American colophony derivatives as well as French tall oil colophony. The results indicate that tall oil colophony is the strongest sensitising material within the tested group and that the maleic-modified products and the zinc-calcium-resinate are moderate sensitisers. Most of the modified products show a higher sensitising capacity than the genuine resin acids themselves. Cross-reactions between the resin acids and the derivatives are uncommon. Therefore, patch testing with high concentrations of colophony (e.g. 60%) will not help to detect patients with colophony-derivative allergy.
Descriptors (primary) allergens; sensitization; hazard evaluation; colophony
Descriptors (secondary) experimental animals; skin tests; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation