|Document ID (ISN)||53449|
|ISSN - Serial title
||0007-1072 - British Journal of Industrial Medicine
|Convention or series no.
||Gardner M.J., Coggon D., Pannett B., Harris E.C.
||Workers exposed to ethylene oxide: a follow up study
||Dec. 1989, Vol.46, No.12, p.860-865. 10 ref.
||A cohort study has been carried out of 2876 men and women employees from four companies that have produced or used ethylene oxide since the 1950s and from eight hospitals which have had ethylene oxide sterilising units since the 1960s. Industrial hygiene data were not available before 1977, but since then time weighted average exposures have been less than 5ppm in almost all jobs and less than 1ppm in many. Past exposures were probably somewhat higher. In contrast to some previous studies, no clear excess of leukaemia (three deaths observed, 2.09 expected) and no increase in stomach cancer (five deaths observed, 5.95 expected) were found. This discrepancy with earlier reports may be due in part to differences in levels of exposure. Total cancer mortality was similar to that expected from national and local death rates. Some specific cancers showed small excesses but their relevance to ethylene oxide exposure is doubtful. Again, contrary to some earlier reports, no excess of cardiovascular disease was found.
||chemical industry; morbidity; carcinogenic effects; hospitals; ethylene oxide
||mortality; comparative study; long-term study; exposure evaluation
||D - Periodical articles
|Broad subject area(s)
Health care services