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Document ID (ISN)53266
CIS number 90-196
ISSN - Serial title Cahiers de notes documentaires - Sécurité et hygiène du travail
Year 1989
Convention or series no.
Author(s) Garnier R., Rousselin X., Rosenberg N.
Title Formaldehyde - A review of the literature
Original title Toxicité de l'aldéhyde formique - Une revue bibliographique [in French]
Bibliographic information 1st Quarter 1989, No.134, Note No.1720-134-89, p.63-85. 203 ref.
Abstract After a brief reminder of the sources of occupational exposure to formaldehyde, this paper reviews existing literature on the toxicity of formaldehyde: toxicokinetics and metabolism, experimental toxicity and toxicity in man (acute toxicity, delayed toxicity, mutagenicity, carcinogenicity and reproductive effects). The study shows that formaldehyde is a powerful mutagen and that it has a carcinogenic effect in the rat. There is only limited evidence of formaldehyde mutagenicity or carcinogenicity in humans.
Descriptors (primary) formaldehyde; chemical products; toxic substances
Descriptors (secondary) mutagenic effects; literature survey; carcinogenic effects; genetic effects; carcinogens
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aldehydes
Genetic factors in reaction to exposures