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Document ID (ISN)53226
CIS number 90-188
ISSN - Serial title 0016-9900 - Gigiena i sanitarija
Year 1988
Convention or series no.
Author(s) Kitaeva L.V., Švarcman P.Ja.
Title Toxicological and hygienic evaluation of inhalation toxicity of formaldehyde
Original title Toksiko-gigieničeskaja ocenka formal'degida pri ingaljacionnom vozdejstvii [in Russian]
Bibliographic information May 1988, No.5, p.75-76. 8 ref.
Abstract The cytogenetic activity of formaldehyde in rat bone marrow was studied after 4 months inhalation exposure to the substance. Formaldehyde concentrations in the exposure chambers were maintained at 0.5mg/m3 (current USSR MAC) and 1.5mg/m3. Formaldehyde increased the frequency of chromosome damage (aberration rate). The findings suggest that the existing USSR MAC for formaldehyde in workplace air of 0.5mg/m3 cannot be viewed as genetically safe and needs revising.
Descriptors (primary) threshold limit values; formaldehyde; inhalation toxicity; genetic effects; USSR
Descriptors (secondary) toxicity evaluation; analysis of chromosome aberrations; cytogenetic studies; animal experiments
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Aldehydes
Genetic factors in reaction to exposures
Occupational exposure limits