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Document ID (ISN)53219
CIS number 90-228
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1989
Convention or series no.
Author(s) Wiklund K., Dich J., Holm L.E., Eklund G.
Title Risk of cancer in pesticide applicators in Swedish agriculture
Bibliographic information Nov. 1989, Vol.46, No.11, p.809-814. Illus. 33 ref.
Abstract The risk of cancer was analysed in a cohort of 20,245 licensed pesticide applicators (99% male) in agriculture who had licences issued between 1965 and 1976. The mean follow up time was 12.2 years. 558 malignant tumours were found (649.8 expected), which resulted in a statistically significantly decreased standardised incidence ratio (SIR) of 0.86 (95% confidence interval (CI):0.79-0.93). Significantly decreased risks of cancer were also found for liver (SIR = 0.45, 95% CI:0.18-0.93), pancreas (SIR = 0.50, 95% CI: 0.26-0.87), lung (SIR = 0.50, 95% CI: 0.35-0.68) and kidney (SIR = 0.53, 95% CI: 0.32-0.84). SIR for testicular cancer was increased (18 cases, SIR = 1.55, 95% CI: 0.92-2.45) and increased with period since licence. For those born in 1935 or later a non-significant increased overall risk of cancer was observed. Comparisons were made with agricultural workers in general since pesticide applicators are mainly farmers that use or have used pesticides to a greater extent. Higher risks for pesticide applicators were found for testicular cancer, tumours of the nervous system and endocrine glands, and Hodgkin's disease.
Descriptors (primary) pesticides; crop protection; neoplasms; carcinogenic effects; agriculture
Descriptors (secondary) Sweden; Hodgkin's disease; long-term study; neuroma; hazard evaluation; testicular cancer
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Agriculture
Agricultural chemicals