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CISDOC database

Document ID (ISN)53216
CIS number 90-125
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1989
Convention or series no.
Author(s) Skyberg K., Hansteen I.L., Jelmert ě., R°nneberg A.
Title A cytogenic and haematological investigation of oil exposed workers in a Norwegian cable manufacturing company
Bibliographic information Nov. 1989, Vol.46, No.11, p.791-798. 23 ref.
Abstract Cytogenetic and haematological parameters were studied in 31 oil exposed workers and 31 office workers matched for age and smoking, all men employed by a Norwegian cable manufacturing company. Information was obtained about tobacco and alcohol consumption, infections, allergies, chronic diseases, use of medicines, and exposure to radiography. A decrease in the absolute lymphocyte counts was observed in the most heavily exposed subgroup (p < 0.05) but no other significant differences were found between exposed workers and referents. The influence of non-occupational variables on the cytogenetic parameters was studied by stepwise multiple linear regression analysis. The frequency of sister chromatid exchanges appeared to be influenced by smoking history (p < 0.05) and season of sampling ( p < 0.01) and, if season was excluded, by age (p < 0.05) and current smoking (p < 0.05). The number of cells with chromosomal aberrations increased with age (p < 0.05) and lymphocyte count ( p < 0.05), whereas the frequency of stable rearrangements was negatively correlated with current smoking (p < 0.01).
Descriptors (primary) lubricants; ropes; electrical industry; haematological effects; genetic effects
Descriptors (secondary) Norway; smoking; comparative study; cytogenetic studies; blood cytology
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Blood diseases
Manufacturing of electrical appliances and equipment
Genetic factors in reaction to exposures
Antifertility and prenatal effects