ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)53086
CIS number 90-202
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1988
Convention or series no.
Author(s) Yardley-Jones A., Anderson D., Jenkinson P.C., Lovell D.P., Blowers S.D., Davies M.J.
Title Genotoxic effects in peripheral blood and urine of workers exposed to low level benzene
Bibliographic information Oct. 1988, Vol.45, No.10, p.694-700. Illus. 22 ref.
Abstract Blood samples were obtained from a population of refinery workers of different age groups. 66 men with low average exposure to benzene and 33 male controls were investigated. An examination of cell cycle kinetics and sister chromatid exchange was carried out which showed no significant differences between groups of individuals varying in their drinking and smoking habits or their exposure to diagnostic x-rays. Individuals with the lowest and highest phenol values were examined for urine mutagenicity, with urinary phenol used here as an indicator of benzene exposure. There were no differences in any of the biochemical measures or haematological parameters investigated in any of the indidivuals except that higher values for mean corpuscular volume were found in exposed than in control individuals.
Descriptors (primary) benzene; perfumes; shipbuilding industry; genetic effects; exposure evaluation
Descriptors (secondary) smoking; toxic substances; age; urinary metabolites; comparative study; sampling and analysis; determination in blood; biochemical tests; determination in urine; length of exposure
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Shipbuliding and ship repair
Aromatic hydrocarbons
Genetic factors in reaction to exposures
Exposure evaluation
Antifertility and prenatal effects