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Document ID (ISN)53012
CIS number 89-1876
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1988
Convention or series no.
Author(s) Steenland K., Schnorr T., Beaumont J., Halperin W., Bloom T.
Title Incidence of laryngeal cancer and exposure to acid mists
Bibliographic information Nov. 1989, Vol.45, No.11, p.766-776. Illus. 23 ref.
Abstract To determine the relation between exposure to acid mist and laryngeal cancer, the smoking habits, drinking habits, and incidence of laryngeal cancer among 879 male steelworkers exposed to acid mists during pickling operations were ascertained. These men had an average duration of exposure of 9.5 years. Exposures to sulfuric acid in the 1970s averaged about 0.2mg/m3, and earlier exposures were probably similar. Nine workers with laryngeal cancer were identified. Using data from national surveys of cancer incidence as referent rates, 3.44 laryngeal cancers would have been expected. Excess smoking by the exposed cohort compared with the United States population resulted in an upward adjustment of the expected number of cases of laryngeal cancer to 3.92. The standardised incidence rate ratio for laryngeal cancer was 2.30 (9/3.92). The finding of excess laryngeal cancer in this cohort is consistent with four other studies published since 1981.
Descriptors (primary) laryngeal cancer; morbidity; iron and steel industry; exposure evaluation; sulfuric acid; aerosols
Descriptors (secondary) USA; smoking; neoplasms; epidemiologic study; length of exposure; toxic substances
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Inorganic substances
Iron and steel industry
Exposure evaluation
Diseases of the respiratory system (except for pneumoconiosis & similar)
Inorganic sulfur compounds