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Document ID (ISN)52332
CIS number 89-1572
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1989
Convention or series no.
Author(s) Venables K.M.
Title Low molecular weight chemicals, hypersensitivity, and direct toxicity: the acid anhydrides
Bibliographic information Apr. 1989, Vol.46, No.4, p.222-232. Illus. 112 ref.
Abstract The acid anhydrides are a group of reactive chemicals used widely in alkyd and epoxy resins. The major hazards to health are mucosal and skin irritation and sensitisation of the respiratory tract. Most cases of occupational asthma caused by acid anhydrides appear to be immunologically mediated. Immunological mechanisms are proposed to explain an influenza-like syndrome and pulmonary haemorrhage, but direct toxicity may also be important in the aetiology of these conditions.
Descriptors (primary) toxic effects; sensitization dermatitis; plastics industry; immunology; hypersensitivity; carboxylic acid anhydrides
Descriptors (secondary) irritants; influenza; serological reactions; human experiments; asthma
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Influenza
Skin diseases
Plastics industry
Bacterial and parasitic diseases
Chemical industry
Viral diseases (other than aids)