ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)52144
CIS number 89-1269
ISSN - Serial title 0323-9179 - Problemi na higienata
Year 1987
Convention or series no.
Author(s) Mečkov G., Petkova V., Zahariev N.
Title Bromsulfalein clearance in persons in professional contact with pesticides
Original title Klirăns na bromsulfaleina u lica văv profesionalen kontakt s pesticidi [in Bulgarian]
Bibliographic information Aug. 1987, Vol.12, p.99-103. Illus. 2 ref.
Abstract In 46 persons, bromsulfalein clearance was followed during a season of work with pesticides. The mean value of bromsulfalein clearance (8,91%) was lower than that of a referent group of healthy persons (14,5%). In 14 of the exposed group the clearance values were under 10%. The changes in clearance do not correlate closely with other indices of liver function. Bromsulfalein metabolism, like pesticide metabolism, probably involves the glutathione-S-transferase system. This makes the measurement of bromsulfalein clearance useful in assessing the effect of pesticides on persons who work with them.
Descriptors (primary) metabolic process; agriculture; pesticides; enzyme disturbances
Descriptors (secondary) biochemical tests; metabolic studies
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals
Blood diseases