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Document ID (ISN)51992
CIS number 89-1191
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1988
Convention or series no.
Author(s) Ribak J., Lilis R., Suzuki Y., Penner L., Selikoff I.J.
Title Malignant mesothelioma in a cohort of asbestos insulation workers: Clinical presentation, diagnosis, and cause of death
Bibliographic information Mar. 1988, Vol.45, No.3, p.182-187. Illus. 33 ref.
Abstract A cohort of 17,800 asbestos insulation workers in the USA and Canada was enrolled for prospective study on 1.01.67 and followed up to the present. Altogether, 356 workers had died of malignant mesothelioma by 1984; 134 of pleural and 222 of peritoneal mesothelioma. The time elapsed from onset of exposure to the development of first symptoms was longer in the group with peritoneal mesothelioma. The most effective approach to the diagnosis of malignant pleural mesothelioma was by open lung biopsy; exploratory laparotomy was the test for diagnosing peritoneal mesothelioma. Patients with pleural mesothelioma died mostly from pulmonary insufficiency whereas those with peritoneal mesothelioma succumbed after a period of pronounced wasting.
Descriptors (primary) mesothelioma; asbestos; exposure evaluation; insulating work; mortality
Descriptors (secondary) Canada; USA; symptoms; pleural mesothelioma; neoplasms; peritoneal mesothelioma; long-term study; long-term exposure; lung biopsy; diagnosis
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Surface treatment
Exposure evaluation
Asbestos