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CISDOC database

Document ID (ISN)51954
CIS number 89-805
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1989
Convention or series no.
Author(s) Donna A., Crosignani P., Robutti F., Betta P.G., Bocca R., Mariani N., Ferrario F., Fissi R., Berrino F.
Title Triazine herbicides and ovarian epithelial neoplasms
Bibliographic information Feb. 1989, Vol.15, No.1, p.47-53. 20 ref.
Abstract The possible role of a class of herbicides, triazines, in ovarian carcinogenesis has been evaluated in a population-based case-referent study. Women previously exposed to triazines showed a significant relative risk of 2.7 for ovarian neoplasms. Although none of the doses could be quantified for the study subjects, 2 risk trends in favour of the plausibility of the association were found: the first by duration and the second by probability of exposure. The population representativity of the study and the comparability of information between the cases and referents suggest the lack of any major bias in the results. Triazine-related risk remained consistent when the analysis was restricted to farmers and when the exposure to other herbicides and to other types of cultivation were considered. Unexposed farmers had the same risk as unexposed non farmers.
Descriptors (primary) agricultural chemicals; herbicides; agriculture; triazines; ovarian cancer
Descriptors (secondary) diseases of genital organs; atrazine; comparative study; epidemiologic study; simazine
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the reproductive system
Heterocyclic compounds
Agriculture
Agricultural chemicals