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Document ID (ISN)51829
CIS number 89-880
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1987
Convention or series no.
Author(s) Gurova A.I., Drozzina N.A., Smoljar N.Ja., Zasorina I.N.
Title Basis for maximum allowable concentration for chrysanthemic acid, chrysanthemic ethyl ester and chrysanthemic chloranhydride in workplace air
Original title Materialy k obosnovaniju PDK hrizantemovoj kisloty, ėtilovogo ėfira i hlorangidrida v vozduhe rabočej zony [in Russian]
Bibliographic information July 1987, No.7, p.53-54. Illus. 3 ref.
Abstract Chrysanthemic acid, ethyl chrysanthemate and chrysanthemoyl chloride - intermediates in the industial synthesis of the new insecticide neopyamine - were studied in animal experiments. The compouds are of moderate toxicity on intragastric administration, are only slightly absorbed by the skin, produce moderate irritation and do not provoke sensitisation. Of the 3, chrysanthemoyl chloride was the most toxic (LD50 = 160mg/kg, mouse) but was not embryotoxic or teratogenic. Maximum allowable concentrations of 10mg/m3 for chrysanthemic acid and ethyl chrysanthemate and 2mg/m3 for chrysanthemoyl chloride are proposed.
Descriptors (primary) chrysanthemoyl chloride; chrysanthemic acid; hazard evaluation; insecticides; ethyl chrysanthemate
Descriptors (secondary) threshold limit values; USSR; determination in air; animal experiments; lethal dose 50; toxic substances
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals
Risk evaluation
Esters and salts