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Document ID (ISN)51811
CIS number 89-923
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1987
Convention or series no.
Author(s) Ladnova G.G.
Title Morphocytochemical studies of peripheral blood leukocytes in mechanics exposed to pesticides
Original title Morfocitohimičeskie issledovanija lejkocitov periferičeskoj krovi mehanizatorov rabotavših s pesticidami [in Russian]
Bibliographic information Aug. 1987, No.8, p.8-11. Illus. 7 ref.
Abstract Medical examinations of 206 mechanics aged 20-50 years occupationally exposed during 4 years to various groups of pesticides revealed morphocytochemical changes in neutrophilic leukocytes which were characterised by toxic granularity, decreases in glycogen and lipid content, inhibition of redox enzymes (myeloperoxidase and acid phosphatase), and increase in alkaline phosphatase activity. A decrease in acid phosphatase and increases in lactate and succinate dehydrogenesis were also identified in lymphocytes. These changes in peripheral leukocytes show the high sensivity of the blood to pesticide exposure and can be used as diagnostic criteria.
Descriptors (primary) pesticides; haematological effects; exposure evaluation; agricultural operations
Descriptors (secondary) medical examinations; agricultural chemicals
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals
Exposure evaluation
Blood diseases