|Document ID (ISN)||51628|
|Convention or series no.
||IARC Monographs 44
||IARC monographs on the evaluation of carcinogenic risks to humans - Alcohol drinking
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1988. Vol.44. 416p. Bibl. Price: CHF 65.00.
||On the basis of its evaluation of the related available toxicological data, IARC states that: (1) there is sufficient evidence for the carcinogenicity of acetaldehyde (the major metabolite of ethanol) in experimental animals; (2) there is inadequate evidence for the carcinogenicity of ethanol and of alcoholic beverages in animals; (3) there is sufficient evidence for the carcinogenicity of alcoholic beverages in humans: the occurrence of malignant tumours of the oral cavity, pharynx, larynx, ¿sophagus and liver is causally related to the consumption of alcoholic beverages; (4) alcoholic beverages are carcinogenic in humans (Group 1).
||carcinogens; IARC; neoplasms; alcoholism; toxicity evaluation; ethanol
||neurotoxic effects; literature survey; acetaldehyde; human experiments; hazard evaluation; epidemiologic study; animal experiments; liver cancer
||E - Books, reports, proceedings
||Psychology and sociology
|Broad subject area(s)
||Stress, psychosocial factors
||Alcohol and drug abuse