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Document ID (ISN)51628
CIS number 89-1050
ISBN(s) 91-832-1244-4
Year 1988
Convention or series no. IARC Monographs 44
Title IARC monographs on the evaluation of carcinogenic risks to humans - Alcohol drinking
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1988. Vol.44. 416p. Bibl. Price: CHF 65.00.
Abstract On the basis of its evaluation of the related available toxicological data, IARC states that: (1) there is sufficient evidence for the carcinogenicity of acetaldehyde (the major metabolite of ethanol) in experimental animals; (2) there is inadequate evidence for the carcinogenicity of ethanol and of alcoholic beverages in animals; (3) there is sufficient evidence for the carcinogenicity of alcoholic beverages in humans: the occurrence of malignant tumours of the oral cavity, pharynx, larynx, ¿sophagus and liver is causally related to the consumption of alcoholic beverages; (4) alcoholic beverages are carcinogenic in humans (Group 1).
Descriptors (primary) carcinogens; IARC; neoplasms; alcoholism; toxicity evaluation; ethanol
Descriptors (secondary) neurotoxic effects; literature survey; acetaldehyde; human experiments; hazard evaluation; epidemiologic study; animal experiments; liver cancer
Document type E - Books, reports, proceedings
Subject(s) Psychology and sociology
Broad subject area(s) Stress, psychosocial factors
Browse category(ies) Alcohols
IARC Monographs
Alcohol and drug abuse