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Document ID (ISN)51534
CIS number 89-545
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1986
Convention or series no.
Author(s) Plastinina R.A., Pavlova G.V., Olejnik N.A., Oščepkov V.I., Šinkareva I.A.
Title Some parameters of respiratory function, blood, and immunity in workers handling isocyanates
Original title Nekotorye pokazateli funkcii dyhanija, krovi i immuniteta u rabotajuščih s izocianatami [in Russian]
Bibliographic information Dec. 1986, No.12, p.16-20. Illus. 9 ref.
Abstract Medical examinations of workers engaged in plastics manufacture and exposed to isocyanates included respiratory function, blood and other laboratory tests and examination of immune status. After 3 years of isocyanate exposure the primary decompensation of functions was replaced by stable compensation. On prolonged exposure, tolerance of the allergenic action of isocyanates, with preservation of high immunological reactivity, was detected. Allergic respiratory disorders are reversible. General toxic, irritant and fibrogenic actions of isocyanates are in proportion to length of exposure.
Descriptors (primary) allergens; irritants; diphenylmethane diisocyanate; allergic respiratory disorders; tolylene diisocyanate; immunobiological changes; chemical industry
Descriptors (secondary) carbon monoxide; hydrofluoric acid; medical examinations; 2,4-tolylene diisocyanate; length of exposure; diphenylmethane diisocyanate (unsp)
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Cyano compounds
Chemical industry