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Document ID (ISN)51402
CIS number 89-531
ISSN - Serial title 0016-9900 - Gigiena i sanitarija
Year 1987
Convention or series no.
Author(s) Bezrukavnikova L.M., Gladkova E.V.
Title State of lipid peroxidation and antioxidant protection systems in workers engaged in manufacturing graphic products
Original title Sostojanie sistem perekisnogo okislenija lipidov i antioksidantnoj zaščity u rabočih proizvodstva grafitovyh izdelij [in Russian]
Bibliographic information Apr. 1987, No.4, p.33-36. Illus. 13 ref.
Abstract Medical examination of workers exposed to coke and graphite dusts with adsorbed polycyclic aromatic hydrocarbon showed activation of the systems of lipid peroxidation, with an increased content of lipid peroxides and intense chemiluminescence in their blood. These changes were observed in workers without pulmonary disorders and with bronchitis of stages I and II. There was no decrease of serum tocopherol level in either group; a compensatory increase was observed in patients with stage I bronchitis and in workers without bronchopulmonary pathology. Under more intense impact of occupational factors as well as in later stages of the disease, exhaustion of the lipid antioxidant system was observed. Such studies can be used to detect workers at risk of developing chronic bronchitis and tumours of the bronchopulmonary system.
Descriptors (primary) lipid peroxides; lipid metabolism; aromatic hydrocarbons; bronchitis; occupational hygiene evaluation; benzo(a)pyrene; carbon products; graphite; metabolic disturbances
Descriptors (secondary) coke; threshold limit values; chronic bronchitis; lung diseases; neoplasms; graphite pneumoconiosis; metabolic studies; occupational medicine; pitch
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Blood diseases
Aromatic hydrocarbons
Diseases of the respiratory system (except for pneumoconiosis & similar)
Endocrine diseases