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Document ID (ISN)50916
CIS number 88-1883
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1988
Convention or series no.
Author(s) Armstrong B.K., De Klerk N.H., Musk A.W., Hobbs M.S.T.
Title Mortality in miners and millers of crocidolite in Western Australia
Bibliographic information Jan. 1988, Vol.45, No.1, p.5-13. Illus. 28 ref.
Abstract 6,505 men and 411 women were employed in the mining and milling of crocidolite in a mine in Western Australia between 1943-1966. Employment was usually brief (median duration: 4 months) and exposure intense (median cumulative exposure: 6 fibres/cc yrs). The Standardised Mortality Ratio (SMR) for all causes in men was 1.53. Statistically significant excess death rates were observed in men for neoplasms, particularly malignant mesothelioma (32 deaths), neoplasms of the trachea, bronchus, and lung (SMR 2.64) and of the stomach (SMR 1.90); respiratory diseases, particularly pneumoconiosis (SMR 25.5); infections, particularly tuberculosis (SMR 4.09); mental disorders, particularly alcoholism (SMR 4.87); digestive diseases, particularly peptic ulceration (SMR 2.46) and cirrhosis of the liver (SMR 3.94); and injuries and poisonings, particularly non-transport accidents (SMR 2.36). The excess mortality from pneumoconiosis, malignant mesothelioma, and respiratory cancers, but not stomach neoplasms, was dependent on time since first exposure and on cumulative exposure. There was no significant increase in mortality from laryngeal cancer (SMR 1.09) or neoplasms other than those listed. In women, the SMR for all causes was 1.47 (95% confidence interval 0.98-2.21) and for neoplasms 1.99.
Descriptors (primary) occupational diseases; crocidolite; mining industry; asbestos mining; milling industry; mortality
Descriptors (secondary) poisoning; neoplasms; Australia; mineral dust pneumoconiosis; tuberculosis; parasitic diseases; digestive system diseases; alcoholism; mental disorders; infectious diseases; tracheal cancer; bronchial cancer; respiratory diseases; lung cancer; peptic ulcer; gastrointestinal cancer; suicide; cirrhosis; injuries; exposure evaluation; long-term study; long-term exposure; evaluation of results; health hazards; length of exposure; dose-response relationship; occupational accidents
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Bacterial and parasitic diseases
Alcohol and drug abuse
Mining and quarrying
Food industry