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CISDOC database

Document ID (ISN)50843
CIS number 88-1885
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1988
Convention or series no.
Author(s) McDuffie H.H., Klaassen D.J., Cockcroft D.W., Dosman J.A.
Title Farming and exposure to chemicals in male lung cancer patients and their siblings
Bibliographic information Jan. 1988, Vol.30, No.1, p.55-59. Illus. 33 ref.
Abstract Retrospective questionnaire study concerning farming and exposure to chemicals of 165 male lung cancer patients (mean age 64.2) and 165 closest in age male siblings (mean age 64.5). The patients were diagnosed as having primary lung cancer between January 1, 1979 and November 1, 1983. Among the lung cancer patients, 38.5% had a same-sex sibling eligible for inclusion and of these, 62.0% responded to the questionnaire. Mean peak years of smoking for patients was 41.0 (n = 135) and among the siblings 36.9 (118) (p<.002). The occupation of farming was present in 47.8% of 163 patients with known occupations as compared to 37.6% of 155 siblings with known occupations (not significant). Patients were consistently exposed more frequently to herbicides (p = .05), grains (p<.015), and diesel fuels (p<.005), and were consistently exposed to greater numbers of chemicals than were siblings (p<.005). These findings raise the possibility that, in addition to smoking, farming and related exposures could be implicated in the aetiology of lung cancer in men.
Descriptors (primary) agricultural chemicals; agriculture; lung cancer
Descriptors (secondary) Canada; seeds; smoking; long-term study; toxic substances; motor fuel; questionnaire survey; pesticides
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Agricultural chemicals
Diseases of the respiratory system (except for pneumoconiosis & similar)