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Document ID (ISN)50629
CIS number 88-2018
ISSN - Serial title 0097-6326 - Federal Register
Year 1986
Convention or series no.
Author(s)
Environmental Protection Agency
Title Guidelines for mutagenicity risk assessment [USA]
Bibliographic information 24 Sep. 1986, Vol.51, No.185, p.34006-34012. 28 ref.
Abstract These guidelines are non-binding policy statements, with no direct effect on the regulated community. It is emphasised that risk assessment is on a case-by-case basis, giving full consideration to all relevant scientific information. Contents: discussion of concepts related to heritable mutagenic risk; test systems; qualitative assessment (hazard identification): mutagenic activity, chemical interactions in the mammalian gonad, weight-of-evidence determination; quantitative assessment (dose response, exposure assessment, risk characterisation).
Descriptors (primary) mutagens; USA; evaluation of results; mutagenicity tests; chemical hazards; hazard evaluation
Descriptors (secondary) exposure evaluation; directive; dose-response relationship; animal experiments
Document type F - Information notes, codes of practice, standards
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation