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Document ID (ISN)50465
CIS number 88-1726
ISSN - Serial title 0140-6736 - Lancet
Year 1987
Convention or series no.
Author(s) Follett E.A.C., Symington I.S., Cameron M.G.
Title Experience with hepatitis B vaccination in nurses in a hospital for the mentally handicapped
Bibliographic information 26 Sept. 1987, Vol.II, No.8561, p.728-731. 11 ref.
Abstract 500 nurses in a large hospital received a full course of hepatitis B vaccination. 480 of them (96%) had detectable antibodies 9 months after starting vaccinations, with high titres (over 1000 IU/L) in 60%. In only 2 of the 20 non-responders did lasting immunity develop with a 4th dose of vaccine. Antibody titre decreased rapidly in all vaccinees followed up. In vaccinees with a titre above 100 IU/L the decrease in titre could be reversed by a booster dose. Those with a titre below 100 IU/L had a variable response to a booster dose and lasting immunity developed in only a few. A recall system was started in order to maintain a protective level of antibodies in the nurses.
Descriptors (primary) infectious hepatitis; vaccination; nursing personnel; hospitals
Descriptors (secondary)
Document type D - Periodical articles
Subject(s) Commerce, services, offices
Broad subject area(s) Biological hazards
Browse category(ies) Liver diseases
Health care services
Bacterial and parasitic diseases
Viral diseases (other than aids)