Document ID (ISN) | 50443 |
CIS number |
88-1592 |
ISSN - Serial title |
Occupational Health Journal |
Year |
1987 |
Convention or series no. |
|
Author(s) |
Kohno K., Yoshida Y., Hirota T., Doi K. |
Title |
Health surveillance of hydrofluoric acid workers - Urinary fluoride monitoring and fluoride clearance in the aging kidney |
Original title |
Fussan sagyōsha no kenkō kanri ni kansuru kenkyū - Seibutsugaku-teki shihyō to shite no nyōchū fusso nōdo to jinkinō no kankei, toku ni nenrei no eikyō ni tsuite [in Japanese] |
Bibliographic information |
May 1987, Vol.10, No.3, p.26-33. Illus. 23 ref. |
Abstract |
Pre-workshift and post workshift fluoride concentrations were measured in urine samples from electronics industry workers who used hydrofluoric acid in the manufacture of television picture tubes, integrated circuits and other components. There was a linear relationship between post-workshift urinary fluoride concentration and HF concentration in the air. A mean urinary fluoride concentration of 4ppm corresponded to an atmospheric HF concentration of 3ppm, which is the Maximal Allowable Concentration recommended by the Japanese Association of Industrial Health and also the Threshold Limit Value suggested by the American Conference of Governmental Industrial Hygienists. A cross-sectional analysis of healthy subjects by 10-year age groups showed a progressive linear decline in creatinine clearance and fluoride clearance (CF). The 24-hour excretion of fluoride and CF were well correlated with each other after fluoride administration. Thus, exposure to HF can be monitored by measuring urinary fluoride. Renal fluoride clearance decreases not only with progression of kidney disease but also with advancing age. |
Descriptors (primary) |
hydrofluoric acid; electronics industry; urine monitoring; exposure tests; age-linked differences |
Descriptors (secondary) |
renal dysfunction |
Document type |
D - Periodical articles |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Inorganic substances Manufacturing of electrical appliances and equipment Biological monitoring Halogens and their inorganic compounds Electronics industry
|