ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)50210
CIS number 88-1198
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1987
Convention or series no.
Author(s) Enterline P.E., Marsh G.M., Esmen N.A., Henderson V.L., Callahan C.M., Paik M.
Title Some effects of cigarette smoking, arsenic, and SO2 on mortality among US copper smelter workers
Bibliographic information Oct. 1987, Vol.29, No.10, p.831-838. 19 ref.
Abstract This is a report on the 1949-1980 mortality experience of 6,078 white male workers who worked for at least 3yrs between 1 January 1946 and 31 December 1976 at 1 or more of 8 copper smelters. The completeness of the cohort was verified statistically, and worker exposures to arsenic, SO2, dust, nickel, cadmium, and lead were estimated from retrospective surveys. By using internal controls, a dose-response relationship for lung cancer was observed with exposure to arsenic and SO2. When cigarette smoking data were included with arsenic and SO2 exposure data in a nested case-control analysis, only smoking and arsenic were statistically significant factors. The arsenic-lung cancer relationship was confined to a single smelter where the raw materials had a high arsenic content. In the remaining smelters, mortality for all causes of death and for all cancer was not high based on comparisons with national, state, and local rates.
Descriptors (primary) USA; arsenic; copper ores; smelting plants; mortality; sulfur dioxide; smoking
Descriptors (secondary) report; lung cancer; neoplasms; statistical aspects; dose-response relationship
Document type D - Periodical articles
Subject(s) Metal production and metalworking
Broad subject area(s) Industries and occupations
Browse category(ies) Inorganic substances
Arsenic and compounds
Smoking
Inorganic sulfur compounds
Smelting and refining operations