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CISDOC database

Document ID (ISN)49692
CIS number 88-909
ISSN - Serial title 0003-9896 - Archives of Environmental Health
Year 1987
Convention or series no.
Author(s) Brownson R.C., Chang J.C.
Title Exposure to alcohol and tobacco and the risk of laryngeal cancer
Bibliographic information July-Aug. 1987, Vol.42, No.4, p.192-196. 31 ref.
Abstract The association between various risk factors and laryngeal cancer was evaluated using a case-control design. The analysis was limited to white males and included 63 cases and 200 controls. The odds ratios associated with previous tobacco use, adjusted for age and alcohol use, followed an increasing linear trend. Similarly, a dose-response relation between alcohol use and laryngeal cancer was identified. The risk for laryngeal cancer was increased synergistically by alcohol and tobacco. After controlling for alcohol and tobacco, the only occupational category with an elevated risk was non-construction labourers. Further studies of the interaction between alcohol and tobacco, occupational factors, and laryngeal cancer aetiology are suggested.
Descriptors (primary) ethanol; hazard evaluation; laryngeal cancer; smoking
Descriptors (secondary) case study; dose-response relationship; synergism
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Risk evaluation