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CISDOC database

Document ID (ISN)49278
CIS number 88-584
ISBN(s) 92-4-154262-4
Year 1987
Convention or series no. Environmental Health Criteria 62
Title 1,2-Dichloroethane
Bibliographic information World Health Organization, Distribution and Sales Services, 1211 Genève 27, Switzerland, 1987. 90p. Bibl.
Abstract This evaluation of toxicity data includes: identification, properties and analysis; sources, transport and distribution; levels of human exposure; kinetics and metabolism; effects on organisms and animals; effects on man; evaluation of health risks for man; recommendations. Repeated inhalation exposure to 40-800mg/m3 may lead to central nervous system depression and gastrointestinal and liver abnormalities. 1,2-dichloroethane is carcinogenic for rats and mice when administered by gavage. 1,2-dichloroethane should therefore be considered as presenting a carcinogenic risk to man. Levels in the environment should be kept as low as feasible.
Descriptors (primary) WHO; hazard evaluation; toxicology; dichloroethane
Descriptors (secondary) mutagenic effects; metabolic process; 1,2-dichloroethane; animal experiments; criteria document; health hazards; biological effects; carcinogenic effects; teratogenic effects
Document type F - Information notes, codes of practice, standards
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
Halogenated hydrocarbons
Genetic factors in reaction to exposures