Document ID (ISN) | 49196 |
CIS number |
88-531 |
ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
Year |
1987 |
Convention or series no. |
|
Author(s) |
Ivanova O.P., Manenko A.K. |
Title |
Bases for a MAC for vinyl phosphate in workplace air |
Original title |
Materialy k obosnovaniju PDK vinilfosfata v vozduhe rabočej zony [in Russian] |
Bibliographic information |
Jan. 1987, No.1, p.47-49. 7 ref. |
Abstract |
Vinyl phosphate (VP) (insecticide) toxicity was tested on mice, rats and guinea pigs in acute and chronic experiments in order to determine an occupational exposure limit. The compound displayed low toxicity when administered orally, by inhalation or percutaneously. Lim(ac), Lim(ch) and Lim(sp) upon inhalation exposure were 94.88, 10.54 and 31.6mg/m3, respectively. LD50 for different species studied ranged from 1170.8 to 2480mg/kg. No sensitising effects were observed. The VP preparation's cumulative effects subsided with the lowering of the daily dose. A MAC of 1mg/m3 (vapour + aerosol) was proposed and approved (hazard class III). |
Descriptors (primary) |
threshold limit values; insecticides; vinyl phosphate; USSR |
Descriptors (secondary) |
toxic effects; acute toxicity; toxicology; toxic substances; pesticide production; lethal dose 50; determination of exposure limits; chronic toxicity; cumulative properties; animal experiments |
Document type |
D - Periodical articles |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Agricultural chemicals Occupational exposure limits Esters and salts
|