| Document ID (ISN) | 48941 |
| CIS number |
88-254 |
| ISSN - Serial title |
0016-9900 - Gigiena i sanitarija |
| Year |
1986 |
| Convention or series no. |
|
| Author(s) |
Žmin'ko P.G. |
| Title |
Characteristics of the toxic action of cyclofos under conditions of continuous and intermittent exposure |
| Original title |
Osobennosti toksičeskogo dejstvija ciklofosa v uslovijah monotonnogo i intermittirujuščego vozdejstvija [in Russian] |
| Bibliographic information |
Aug. 1986, No.8, p.42-44. Illus. 4 ref. |
| Abstract |
Continuous intratracheal administration of cyclofos caused a more pronounced toxic effect than intermittent administration did. Inhibition of the monooxygenase enzyme system of the liver and lungs was observed on continuous exposure, and induction of this system with more evident changes in lungs on intermittent exposure. The results were used as a basis for a MAC for cyclofos in workplace air for agriculture of 0.5mg/m3 (vapour + aerosol), with indication "penetrates through skin; hazard class 2". |
| Descriptors (primary) |
threshold limit values; USSR; hepatotoxic effects; cyclofos; pneumotoxic effects; insecticides; toxicology; toxic hepatitis; pesticides |
| Descriptors (secondary) |
animal experiments; enzyme inhibition |
| Document type |
D - Periodical articles |
| Subject(s) |
Agriculture, fishing, animal husbandry
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Agricultural chemicals
Occupational exposure limits
Liver diseases
Esters and salts
|
