|Document ID (ISN)||48882|
|ISSN - Serial title
||0003-4878 - Annals of Occupational Hygiene
|Convention or series no.
||Seniori Costantini A., Paci E., Scala D., Cariaggi P., Cipparrone G., Confortini M., Maddau C., Butt R., Dolara P., Salvadori M., Caderni G.
||Monitoring of carcinogenic risks in tannery workers by means of desquamative lung and bladder cytology and urinary mutagenicity
||1986, Vol.31, No.1, p.21-30. Illus. 18 ref.
||Proportional mortality data on a cohort of tannery workers showed an increased risk of lung cancer, oesophageal cancer, sarcomas and leukaemias. From a cohort of workers and controls in the same area, data were obtained on urinary mutagenic activity using Salmonella typhimurium TA1538 and TA100 as tester strains, with and without metabolic activation. The mutagenic activity of the urine of tanning workers did not differ from that of clerical workers. Bladder desquamative cytology did not show any difference between clerical controls and workers. Pulmonary cytology specimens were normal or showed cellular atypical metaplasia. No cases with atypical cells or obvious neoplastic changes were found. The relative risk of pathological lung cytology was higher in chemical refining than in mechanical refining and tanning.
||mutagenic effects; carcinogens; lung cancer; sputum cytology; tanning industry; urine cytology; exposure evaluation
||epidemiologic study; mortality
||D - Periodical articles
||Leather, fur and footwear
|Broad subject area(s)
||Industries and occupations
||Antifertility and prenatal effects
Diseases of the respiratory system (except for pneumoconiosis & similar)
Footwear, leather and fur industry
Genetic factors in reaction to exposures