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Document ID (ISN)48774
CIS number 87-1425
ISBN(s) 91-7464-311-8
Year 1986
Convention or series no. Arbete och Hälsa 1986:25
Author(s) Zahlsen K., Nilsen O.G.
Title Nordic Expert Group for Documentation of Occupational Exposure Limits - 69. Acetaldehyde
Original title Nordiska expertgruppen för gränsvärdesdokumentation - 69. Acetaldehyd [in Norwegian]
Bibliographic information Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1986. 45p. Illus. 101 ref.
Abstract A survey of literature on acetaldehyde to serve as background information for a discussion on occupational exposure limits. Exposure to relatively low concentrations of acetaldehyde irritates the mucous membranes of the eyes and the respiratory system. Acetaldehyde has been shown to have genotoxic, teratogenic and carcinogenic eeffects in animal experiments in vivo and/or in vitro. The risk of these effects occurring in humans following occupational exposure is difficult to estimate from the current literature. Further experiments are required if an adequate extrapolation of risk is to be made. It is recommended that an exposure limit be based on the irritant effect of acetaldehyde on the mucous membranes, and that possible genotoxic, teratogenic and carcinogenic eeffects be further investigated.
Descriptors (primary) threshold limit values; irritants; acetaldehyde; carcinogenic effects; determination of exposure limits; genetic effects; teratogenic effects; toxicology
Descriptors (secondary) literature survey; Nordic Countries; criteria document; TLV list; animal experiments
Document type F - Information notes, codes of practice, standards
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Occupational exposure limits